Fixed drug reaction
| Fixed drug reaction | |
|---|---|
| Specialty | Dermatology  |
Fixed drug reactions, also known as fixed drug eruptions, are common and so named because they recur at the same site with each exposure to a particular medication.[1] Medications inducing fixed drug eruptions are usually those taken intermittently.[1]
Contents
1 Signs and symptoms
2 Cause
3 See also
4 References
5 External links
Signs and symptoms
A painful purple patch of skin that occurs in the same location with repeated exposures to the culprit drug is the classic presentation of a fixed drug reaction. The lips, genitals, and hands are often involved.
Cause
Medications that are commonly implicated as a cause of fixed drug eruptions include the following:
- Fluconazole
- Ciprofloxacin
- Doxycycline
- Clarithromycin
NSAIDs (e.g., ibuprofen)- Trimethoprim
- Cotrimoxazole
- Phenytoin
- Cetirizine
Pseudoephedrine[2]
See also
- List of cutaneous conditions
- List of human leukocyte antigen alleles associated with cutaneous conditions
References
^ ab James, William; Berger, Timothy; Elston, Dirk (2005). Andrews' Diseases of the Skin: Clinical Dermatology (10th ed.). Saunders. p. 127. ISBN 0-7216-2921-0..mw-parser-output cite.citation{font-style:inherit}.mw-parser-output q{quotes:"""""""'""'"}.mw-parser-output code.cs1-code{color:inherit;background:inherit;border:inherit;padding:inherit}.mw-parser-output .cs1-lock-free a{background:url("//upload.wikimedia.org/wikipedia/commons/thumb/6/65/Lock-green.svg/9px-Lock-green.svg.png")no-repeat;background-position:right .1em center}.mw-parser-output .cs1-lock-limited a,.mw-parser-output .cs1-lock-registration a{background:url("//upload.wikimedia.org/wikipedia/commons/thumb/d/d6/Lock-gray-alt-2.svg/9px-Lock-gray-alt-2.svg.png")no-repeat;background-position:right .1em center}.mw-parser-output .cs1-lock-subscription a{background:url("//upload.wikimedia.org/wikipedia/commons/thumb/a/aa/Lock-red-alt-2.svg/9px-Lock-red-alt-2.svg.png")no-repeat;background-position:right .1em center}.mw-parser-output .cs1-subscription,.mw-parser-output .cs1-registration{color:#555}.mw-parser-output .cs1-subscription span,.mw-parser-output .cs1-registration span{border-bottom:1px dotted;cursor:help}.mw-parser-output .cs1-hidden-error{display:none;font-size:100%}.mw-parser-output .cs1-visible-error{font-size:100%}.mw-parser-output .cs1-subscription,.mw-parser-output .cs1-registration,.mw-parser-output .cs1-format{font-size:95%}.mw-parser-output .cs1-kern-left,.mw-parser-output .cs1-kern-wl-left{padding-left:0.2em}.mw-parser-output .cs1-kern-right,.mw-parser-output .cs1-kern-wl-right{padding-right:0.2em}
^ Vidal, Carmen; Pérez-Carral, Celsa; Armisén, Margarita; Prieto, Azucena (1998). "Nonpigmenting Fixed Drug Eruption due to Pseudoephedrine". Annals of Allergy, Asthma & Immunology. 80 (4): 309–10. doi:10.1016/S1081-1206(10)62974-2. PMID 9564979.
External links
| Classification | D
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