磺胺





Confusion grey.svg  提示：本条目的主题不是磺胺类药物。


Disambig gray.svg  本文介紹的是一种有机物。關於有机化学中的官能团，請見「磺酰胺」。

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磺胺

Sulfanilamide-skeletal.svg

Sulfanilamida-3D.png
系统（IUPAC）命名名称

4-aminobenzenesulfonamide

临床数据
Drugs.com
消费者药物信息
识别信息
CAS注册号
63-74-1 ✓
ATC代码
J01EB06 D06BA05 QJ01EQ06
PubChem
CID 5333
DrugBank
DB00259 ✓
ChemSpider
5142 ✓
UNII
21240MF57M ✓
KEGG
D08543 ✓
ChEBI
CHEBI:45373 ✓
ChEMBL（英语：ChEMBL）
CHEMBL21 ✓
NIAID ChemDB（英语：NIAID ChemDB）
019103
化学信息
化学式
C6H8N2O2S
摩尔质量
172.20 g/mol




物理性质
密度
1.08 g/cm3
熔点
165 °C（329 °F）
  (verify)

磺胺（Sulfanilamide），即对氨基苯磺酰胺，是一种具有药用价值的有机物，最早在1908年由奥地利化学家保罗·雅各布·约瑟夫·杰尔莫（Paul Josef Jakob Gelmo）合成，并在1909年获得专利权。磺胺最初是作为一个偶氮类染料的中间体得到合成，但直到20世纪30年代，磺胺的一种衍生物百浪多息得到报道后，人们才开始注意到磺胺类的药用价值。目前的磺胺类药物均是在磺胺的基础上开发出来的[1][2][3][4]。



参见


  • 磺胺类药物


参考文献





  1. ^ Paul Gelmo. Encyclopedia.com. 


  2. ^ Gelmo, Paul. Über Sulfamide der p-Amidobenzolsulfonsäure. Journal für Praktische Chemie. May 14, 1908, 77: 369–382. 


  3. ^ On May 18, 1909, Deutsches Reich Patentschrift number 226,239 for sulfanilamide was awarded to Heinrich Hörlein of the Bayer corporation.


  4. ^ 尤启冬; 等. 药物化学 第7版. 北京: 人民卫生出版社. 2012: 350–355. ISBN 978-7-117-14434-6.  引文格式1维护：显式使用等标签 (link)









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