同源重組
Multi tool use
同源重組（英語：Homologous recombination）是遺傳重組的一種類型，指兩股具有相似序列的DNA的重新排列，使遺傳物質發生交換。可發生於自然界中，或應用於人工的分子生物學技術。
真核生物體內的同源重組過程中發生於減數分裂時期，是染色體互換所造成的結果。除此之外，同源重組也能使遭受損害的染色體，得以利用與自身相似，且未受傷害的另一條染色體，來進行DNA修復作用[1]。細菌的同源重組，則發生於細菌進行接合（conjugation）、转导（transduction）或是转化（transformation）的過程中。
許多技術利用同源重組將基因導入生物個體中，形成重組DNA[2]，方法又稱基因標的（gene targeting）。
参见
參考文獻
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H. Lodish, A. Berk, L.S. Zipursky, P. Matsudaira, D. Baltimore, J. Darnell. Molecular Cell Biology 4th ed. W. H. Freeman and Company. 2000. ISBN 978-0-7167-3136-8. 12.5. Recombination between Homologous DNA Sites: Double-Strand Breaks in DNA Initiate Recombination
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H. Lodish, A. Berk, L.S. Zipursky, P. Matsudaira, D. Baltimore, J. Darnell. Molecular Cell Biology 4th ed. W. H. Freeman and Company. 2000. ISBN 978-0-7167-3136-8.
8.5. Gene Replacement and Transgenic Animals: DNA Is Transferred into Eukaryotic Cells in Various Ways
參見
遗传学：同源重组/可动遗传因子
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主要/原核生物
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存于真核生物
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- 转染
- 染色體互換
- 基因转变
- 融合基因
- 基因水平轉移
- 姐妹染色单体交换
- 转座子
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遗传学索引
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| 描述 |
- 生化
基因表达
转录
- 转录因子与细胞内受体
- 辅调节因子
- RNA
- 重复序列
- 转录后修饰
翻译
DNA/RNA结合蛋白
- 蛋白质
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| 疾病 |
- Replication and repair
- Transcription factor
- Transcription
- Translation
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JQoNY7TLOUfwYAh0uHohw,V1,f,jEOTC,okA 8SsC5QcC
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